Tie2 Kinase Inhibitor - CAS 948557-43-5 - Calbiochem
| Name | Tie2 Kinase Inhibitor - CAS 948557-43-5 - Calbiochem |
|---|---|
| Supplier | EMD Millipore |
| Catalog | 612085 |
| Cas Number | 948557-43-5 |
| Formula | C₂₆H₂₁N₃O₂S |
| Purity | ≥97% by HPLC |
| Description | A cell-permeable pyridinylimidazole compound that acts as a potent, reversible, and ATP-binding site-targeting inhibitor of Tie2 (IC 50 = 250 nM) with ~200-fold selectivity over p38 MAPK and greater than 10-fold selectivity over VEGFR2, VEGFR3, and PDGFR1β |
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