L3MBTL1 Ligand, UNC669 - Calbiochem

Name L3MBTL1 Ligand, UNC669 - Calbiochem
Supplier EMD Millipore
Catalog 442640
Formula C₁₅H₂₀BrN₃O
Purity ≥95% by HPLC
Description A nicotinamido-pyrrolidine compound that targets the second MBT (Malignant Brain Tumor) module of "chromatin lock" L3MBTL1 (Lethal 3 MBT-Like protein 1; K d = 5 µM by Isothermal titration calorimetry) that "reads"/binds mono- and dimethyl-lysine modified histones as well as other proteins involved in transcription, such as p53 and Rb, via methylation-dependent recognition
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