TNAP Inhibitor - CAS 496014-13-2 - Calbiochem
| Name | TNAP Inhibitor - CAS 496014-13-2 - Calbiochem |
|---|---|
| Supplier | EMD Millipore |
| Catalog | 613810 |
| Cas Number | 496014-13-2 |
| Formula | C₁₇H₁₆N₂O₄S |
| Purity | ≥95% by HPLC |
| Description | A cell-permeable quinolinyl-benzenesulfonamide compound that acts as a potent reversible inhibitor against tissue-nonspecific (TN) alkaline phosphatase (AP) activity (IC 50 = 190 nM) with CYP2C19 being the only other known target, while exhibiting little or no inhibitory activity in over 250 assays involving other enzymes, including, but not limited to, placental and intestinal APs (IC 50 >100 µM), PHOSPHO1 phosphatase, and NPP1 phosphodiesterase |
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