InSolution™ STAT3 Inhibitor III, WP1066 - Calbiochem

• Supplier: EMD Millipore
• Catalog: 573129
• Formula: A50mM(5mg/281µl)solutionofSTAT3InhibitorIII,W
• Purity: ≥97% by HPLC
• Description: A cell-permeable AG 490 (Cat. No. 658401) tyrphostin analog that acts as an effective STAT3 pathway inhibitor and a much more potent antitumor agent than AG 490 in inhibiting malignant glioma growth both in cultures in vitro (IC 50 = 5.6 and 3.7 µM in a viability assay using U87-MG and U373-MG, respectively; no inhibition against nontumor NHA at 10 µM) and in mice in vivo