VEGF Inhibitor, V1 - Calbiochem

• Supplier: EMD Millipore
• Catalog: 676495
• Formula: Suppliedasatrifluoroacetatesalt.
• Purity: ≥95% by HPLC
• Description: An NRP-1-binding heptapeptide whose target was initially mistaken as VEGFR2/KDR/Flk-1 due to its binding activity to a CHO-KDR culture that was later shown to express primarily NRP-1 and little KDR. V1/A7R specifically competes against VEGF 165 binding to recombinant NRP-1 in cell-free binding assays (IC 50 = 60 µM), while exhibiting no activity against the interaction between NRP-1 and heparin or VEGF 165 binding to KDR, VEGFR1/Flt-1, and heparin