FGF/PDGF/VEGF RTK Inhibitor - CAS 144335-37-5 - Calbiochem

Name FGF/PDGF/VEGF RTK Inhibitor - CAS 144335-37-5 - Calbiochem
Supplier EMD Millipore
Catalog 341610
Cas Number 144335-37-5
Formula C₁₆H₁₁N₃O₂
Purity ≥95% by HPLC
Description A cell-permeable benzimidazolo-hydroquinolinone compound that acts as a potent, reversible, ATP-competitive inhibitor against PDGFRβ, FGFR-1, and VEGFR-2 (IC 50 = 20, 90, and 240 nM, respectively) and effectively suppresses VEGF-stimulated proliferation of HMVECs (EC 50 = 420 nM).
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