Name | FGF/PDGF/VEGF RTK Inhibitor - CAS 144335-37-5 - Calbiochem |
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Supplier | EMD Millipore |
Catalog | 341610 |
Cas Number | 144335-37-5 |
Formula | C₁₆H₁₁N₃O₂ |
Purity | ≥95% by HPLC |
Description | A cell-permeable benzimidazolo-hydroquinolinone compound that acts as a potent, reversible, ATP-competitive inhibitor against PDGFRβ, FGFR-1, and VEGFR-2 (IC 50 = 20, 90, and 240 nM, respectively) and effectively suppresses VEGF-stimulated proliferation of HMVECs (EC 50 = 420 nM). |
Supplier Page | Shop |