MDM2 Inhibitor, SP-141 - Calbiochem

• Supplier: EMD Millipore
• Catalog: 532814
• Formula: C₂₂H₁₆N₂O
• Purity: ≥97% by HPLC
• Description: A cell-permeable pyrido[3,4-b]indole derivative that binds directly to the hydrophobic groove of MDM2 with high affinity (K i = 28 nM) and inhibits its activity in multiple breast cancer cell lines, independent of their p53 status

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