Name | PARP Inhibitor XIV - CAS 1104546-89-5 - Calbiochem |
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Supplier | EMD Millipore |
Catalog | 528824 |
Cas Number | 1104546-89-5 |
Formula | C₁₅H₁₂N₂O₂ |
Purity | ≥97% by HPLC (sum of two isomers) |
Description | A cell-permeable isoquinolinedione compound that potently inhibits PARP-1 activity (pIC 50 = 7.35; IC 50 = 45 nM) in a NAD + -competitive and reversible manner, while affecting PPAR-2 activity with a 100-fold lower potency |
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