PARP Inhibitor XIV - CAS 1104546-89-5 - Calbiochem

Name PARP Inhibitor XIV - CAS 1104546-89-5 - Calbiochem
Supplier EMD Millipore
Catalog 528824
Cas Number 1104546-89-5
Formula C₁₅H₁₂N₂O₂
Purity ≥97% by HPLC (sum of two isomers)
Description A cell-permeable isoquinolinedione compound that potently inhibits PARP-1 activity (pIC 50 = 7.35; IC 50 = 45 nM) in a NAD + -competitive and reversible manner, while affecting PPAR-2 activity with a 100-fold lower potency
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