UCN-01

• Supplier: EMD Millipore
• Catalog: 539644
• Cas Number: 112953-11-4
• Formula: C₂₈H₂₆N₄O₄
• Purity: ≥95% by HPLC
• Description: A cell-permeable Staurosporine (Cat. No. 569397 ) derived anticancer agent that reversibly and ATP-competitively inhibits several protein kinases (IC 50 = 29 nM, 34 nM, 30 nM, 590 nM and 530 nM for PKCα, PKCβ, PKCγ, PKCδ and PKCε; IC 50 = 7 nM, 27 nM, 50 nM, 50 nM, 150 nM and 1.04 µM for Chk1, Cdc25C-associated protein kinase 1, Cdk1, PAK4, Cdk5/p25 and Chk2; IC 50 = 33 nM, 50 nM, 95 nM, 500 nM, 500 nM and 1.0 µM for PDK1, lck, MAPKAP kinase-2, Akt, GSK-3β and PKA, respectively)

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