Necrostatin-1 - CAS 4311-88-0 - Calbiochem
| Name | Necrostatin-1 - CAS 4311-88-0 - Calbiochem |
|---|---|
| Supplier | EMD Millipore |
| Catalog | 480065 |
| Cas Number | 4311-88-0 |
| Formula | C₁₃H₁₃N₃OS |
| Purity | ≥95% by HPLC |
| Description | A cell-permeable, potent, and selective blocker of necroptosis (EC 50 = 494 nM in FADD-deficient Jurkat cells treated with TNF-α), a nonapoptotic necrotic cell death pathway mediated by death-domain receptors (DRs) that offers neuroprotection in a murine model of ischemic brain injury |
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