Formin FH2 Domain Inhibitor, SMIFH2 - CAS 340316-62-3 - Calbiochem
| Name | Formin FH2 Domain Inhibitor, SMIFH2 - CAS 340316-62-3 - Calbiochem |
|---|---|
| Supplier | EMD Millipore |
| Catalog | 344092 |
| Cas Number | 340316-62-3 |
| Formula | C₁₅H₉BrN₂O₃S |
| Purity | ≥98% by HPLC (sum of two geometrical isomers) |
| Description | A cell-permeable thiooxodihydropyrimidinedione compound that inhibits both formin-mediated, profilin-independent actin nucleation (IC 50 ~15 µM using mDia1 or mDia2) and formin-mediated elongation of actin filaments in the presence of profilin (IC 50 ~4 µM using Cdc12 or mDia2), but not the Arp2/3-mediated or formin-independent actin assembly |
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