TGF-β RI Kinase Inhibitor II - CAS 446859-33-2 - Calbiochem

Name TGF-β RI Kinase Inhibitor II - CAS 446859-33-2 - Calbiochem
Supplier EMD Millipore
Catalog 616452
Cas Number 446859-33-2
Formula C₁₇H₁₃N₅
Purity ≥95% by HPLC
Description A cell-permeable, potent, selective, reversible, and ATP-competitive inhibitor of TGF-β type I receptor (ALK5; IC 50 = 23 nM, 4 nM and 18 nM for ALK5 binding, ALK5 auto-phosphorylation, and TGF-β cellular assay in HepG2 cells, respectively)
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