Name | Cyclopamine-KAAD - Calbiochem |
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Supplier | EMD Millipore |
Catalog | 239804 |
Formula | C₄₄H₆₃N₃O₄ |
Purity | ≥70% by HPLC (sum of two isomers) |
Description | A cell-permeable potent analog of Cyclopamine (Cat. No. 239803) that specifically inhibits Hedgehog (Hh) signaling with similar or lower toxicity (IC 50 = 20 nM in Shh-LIGHT2 assay; 50 nM in p2 Ptch-/- cells; 500 nM in SmoA1-LIGHT cells) |
Supplier Page | Shop |