GW9662 - CAS 22978-25-2 - Calbiochem
| Name | GW9662 - CAS 22978-25-2 - Calbiochem |
|---|---|
| Supplier | EMD Millipore |
| Catalog | 370700 |
| Cas Number | 22978-25-2 |
| Formula | C₁₃H₉ClN₂O₃ |
| Purity | ≥95% by HPLC |
| Description | A cell-permeable, selective, and irreversible PPAPγ antagonist (IC 50 = 3.3 nM, 32 nM, and 2.0 µM for PPARγ, PPARα, and PPARδ, respectively) that is reported to covalently modify a cysteine residue in the binding site of PPAR. At a concentration of 10 µM also acts as an agonist of human pregnane X receptor (PXR) and farnesoid X receptor (FXR) |
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