MEK Inhibitor VIII - CAS 212631-61-3 - Calbiochem
| Name | MEK Inhibitor VIII - CAS 212631-61-3 - Calbiochem |
|---|---|
| Supplier | EMD Millipore |
| Catalog | 444965 |
| Cas Number | 212631-61-3 |
| Formula | C₁₈H₁₆F₃IN₂O₂ |
| Purity | ≥98% by HPLC |
| Description | A cell-permeable and orally available amino-benzamide compound that acts as a potent and non-ATP-competitive inhibitor of MEK1/2 (IC 50 = 8 nM) with an excellent selectivity over ERK, c-Src, Cdk's, and PI 3-Kγ (IC 50 >1.0 µM) |
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