Autotaxin Inhibitor I, S32826 - CAS 1103672-43-0 - Calbiochem
| Name | Autotaxin Inhibitor I, S32826 - CAS 1103672-43-0 - Calbiochem |
|---|---|
| Supplier | EMD Millipore |
| Catalog | 189510 |
| Cas Number | 1103672-43-0 |
| Formula | C₂₁H₃₄NO₄PNa₂•2H₂O |
| Purity | ≥97% by HPLC |
| Description | A phosphonate compound that potently inhibits both the phosphodiesterase (IC 50 = 9 nM in pNppp assay using ATX β) and the lysoPLD (IC 50 = 5.6 nM and 47 nM, by enzyme-linked fluorescence detection or autoradiography by TLC, respectively, using ATX β) activities of ATX α/β/γ, while exhibiting much reduced (IC 50 ~6 µM and 15 µM against Src and PTP-1B, respectively) or little activity toward 29 other receptors and enzymes |
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