JAK2 Inhibitor IV - CAS 1110502-30-1 - Calbiochem
| Name | JAK2 Inhibitor IV - CAS 1110502-30-1 - Calbiochem |
|---|---|
| Supplier | EMD Millipore |
| Catalog | 420139 |
| Cas Number | 1110502-30-1 |
| Formula | C₁₇H₂₀N₄O₂S |
| Purity | ≥97% by HPLC |
| Description | An aminoindazole compound that potently inhibits the activity of both the wild-type JAK2 and the constitutively active V617F mutant (IC 50 = 78 and 206 nM, respectively) frequently found in patients with clonal polycythemia vera, essential thrombocytosis, and chronic idiopathic myelofibrosis, while exhibiting much reduced activity against JAK3 (IC 50 = 2.93 µM). |
| Supplier Page | Shop |
Product images
