Name | TGF-β RI Kinase Inhibitor IX - Calbiochem |
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Supplier | EMD Millipore |
Catalog | 616463 |
Formula | C₁₈H₁₈N₄O₃S |
Purity | ≥95% by HPLC |
Description | A cell-permeable pyridinyloxypyridine compound that acts as a potent and highly selective inhibitor against TGFβ RI/ALK5 (IC 50 = 72 nM, [ATP] = 1 mM) by targeting both the ATP-binding site and the “selectivity pocket”, while exhibiting much reduced or little activity against a panel of 75 other kinases (IC 50 <1 µM) |
Supplier Page | Shop |