Eeyarestatin I - CAS 412960-54-4 - Calbiochem
| Name | Eeyarestatin I - CAS 412960-54-4 - Calbiochem |
|---|---|
| Supplier | EMD Millipore |
| Catalog | 324521 |
| Cas Number | 412960-54-4 |
| Formula | C₂₇H₂₅Cl₂N₇O₇ |
| Purity | ≥90% by HPLC |
| Description | A cell-permeable oxo-imidazolidinyl-hydroxyurea whose cellular metabolite is shown to effectively inhibit the ER membrane translocon sec61 complex-mediated transfer of newly synthesized polypeptide, resulting in a blockage of ER-mediated posttranslational glycosylation and signal peptide removal (Effective conc. = 8 µM in HepG2 and HeLa cultures) |
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