p38 MAP Kinase Inhibitor IV - CAS 1638-41-1 - Calbiochem
| Name | p38 MAP Kinase Inhibitor IV - CAS 1638-41-1 - Calbiochem |
|---|---|
| Supplier | EMD Millipore |
| Catalog | 506153 |
| Cas Number | 1638-41-1 |
| Formula | C₁₂H₄Cl₆O₄S |
| Purity | ≥95% by HPLC |
| Description | A cell-permeable symmetrical sulfone compound that acts as a potent and ATP-competitive inhibitor of p38α/β MAPK (IC 50 = 130 and 550 nM, respectively), while exihibiting much reduced activity (≤23% inhibition at 1 µM) against p38γ/δ, ERK1/2, and JNK1/2/3 |
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