| Name |
InSolution™ Rac1 Inhibitor II, Z62954982 - CAS 1090893-12-1 - Calbiochem
|
| Supplier |
EMD Millipore
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| Catalog |
553512
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| Cas Number |
1090893-12-1
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| Formula |
A100mM(10mg/241µl)solutionofRac1InhibitorII,Z
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| Purity |
≥93% by HPLC
|
| Description |
A cell-permeable isoxazolyl-benzamide compound that is more effective than NSC23766 (Cat. Nos. 553502 & 553508 ) in inhibiting PDGF-BB- (Cat. No. 521225 ) induced cellular Rac1 activation (45.8% vs 11.1% inhibition by 4 h pretreatment of the respective compound at 50 µM) in serum-starved SMCs (human aortic smooth muscle cells) by interfering Rac1-Tiam1 interaction, while exhibiting no effect toward cellular Cdc42 and RhoA activation or Rac1 interaction to its effector Pak1
|
| Supplier Page |
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