eEF-2 Kinase Inhibitor, NH125 - CAS 278603-08-0 - Calbiochem
| Name | eEF-2 Kinase Inhibitor, NH125 - CAS 278603-08-0 - Calbiochem |
|---|---|
| Supplier | EMD Millipore |
| Catalog | 324515 |
| Cas Number | 278603-08-0 |
| Formula | C₂₇H₄₅IN₂ |
| Purity | ≥95% by NMR |
| Description | A cell-permeable imidazolium compound that inhibits the activity of bacterial histidine kinases (EnvZ, PhoQ, BvgS, and EvgS) and eukaryotic eEF-2 (elongation factor 2) kinase/CaMKIII (IC 50 = 60 nM), while exhibiting much lower potency against PKC, PKA, and CaMKII (IC 50 = 7.5, 80, and >100 µM, respectively) |
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