Name | SANT-1 - CAS 304909-07-7 - Calbiochem |
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Supplier | EMD Millipore |
Catalog | 559303 |
Cas Number | 304909-07-7 |
Formula | C₂₃H₂₇N₅ |
Purity | ≥95% by HPLC |
Description | A potent antagonist of the Sonic Hedgehog (Shh) signaling pathway (IC 50 = 20 nM in Shh-LIGHT2 assay and in Ptch1 - l - < cells) that acts by binding to Smoothened (Smo; K D = 1.2 nM), a distant relative of G protein-coupled receptors |
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