SANT-1 - CAS 304909-07-7 - Calbiochem

Name SANT-1 - CAS 304909-07-7 - Calbiochem
Supplier EMD Millipore
Catalog 559303
Cas Number 304909-07-7
Formula C₂₃H₂₇N₅
Purity ≥95% by HPLC
Description A potent antagonist of the Sonic Hedgehog (Shh) signaling pathway (IC 50 = 20 nM in Shh-LIGHT2 assay and in Ptch1 - l - < cells) that acts by binding to Smoothened (Smo; K D = 1.2 nM), a distant relative of G protein-coupled receptors
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