ACE2 Inhibitor, MLN-4760 - CAS 305335-31-3 - Calbiochem
| Name | ACE2 Inhibitor, MLN-4760 - CAS 305335-31-3 - Calbiochem |
|---|---|
| Supplier | EMD Millipore |
| Catalog | 530616 |
| Cas Number | 305335-31-3 |
| Formula | C₁₉H₂₃Cl₂N₃O₄ |
| Purity | ≥97% by HPLC |
| Description | A selective and highly potent inhibitor against ACE2 carboxypeptidase activity (IC 50 = 0.44 nM against 50 pM human ACE2; [ZnCl 2 ] = 10 µM, [MCA-APK(DNP)] = 50 µM) with little potency toward carboxypeptidase A or ACE peptidyldipeptidase activity (IC 50 = 27 µM and >100 µM against 0.5 nM bovine CPDA and 1 nM porcine ACE, respectively; [Substrate] = 50 µM) |
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