GSK3β Inhibitor XIX, IM-12 - Calbiochem

Name GSK3β Inhibitor XIX, IM-12 - Calbiochem
Supplier EMD Millipore
Catalog 361565
Formula C₂₂H₂₀FN₃O₂
Purity ≥95% by HPLC
Description A cell-permeable indolylmaleimide derivative and SB-216763 analog that acts as a GSK-3β inhibitor, with an IC 50 of 53 nM in an in vitro binding assay, compared with 92 nM for SB-216763 in the same assay condition, and reduces GSK-3β activity to 27% in an enzymatic assay at 3 µM concentration
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