S6K1 Inhibitor, PF-4708671 - Calbiochem
| Name | S6K1 Inhibitor, PF-4708671 - Calbiochem |
|---|---|
| Supplier | EMD Millipore |
| Catalog | 559273 |
| Formula | C₁₉H₂₁F₃N₆ |
| Purity | ≥98% by HPLC |
| Description | A cell-permeable piperazinyl-pyrimidine compound that acts as an inhibitor against S6K1 (K i = 20 nM; IC 50 = 160 nM) and MSK1 (IC 50 = 950 nM) kinase activity, exhibiting little or much reduced potency against a panel of 75 other protein kinases (IC 50 = 4.7, 9.2, 65 µM, respectively, against RSK1, RSK2, and S6K2; ≤27% inhibition of the rest at 1 µM) and 10 lipid kinases (≤6% inhibition at 10 µM) |
| Supplier Page | Shop |
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