mTOR Inhibitor IV, Ku-63794 - CAS 938440-64-3 - Calbiochem
| Name | mTOR Inhibitor IV, Ku-63794 - CAS 938440-64-3 - Calbiochem |
|---|---|
| Supplier | EMD Millipore |
| Catalog | 475990 |
| Cas Number | 938440-64-3 |
| Formula | C₂₅H₃₁N₅O₄ |
| Purity | ≥98% by HPLC |
| Description | A cell-permeable pyrido-pyrimidine compound that acts as a highly selective and potent inhibitor against both mTORC1 & mTORC2 (IC 50 = ~10 nM against mTOR activity in raptor or rictor immunoprecipitate from HEK293 with 100 µM ATP), with much reduced potency against MKK1 and PI 3-Kα (IC 50 ~9 µM) and little or no activity toward more than 200 other protein and lipid kinases, including Akt, ATR, DNA-PK, PDK1, and PI 3-Kβ/γ/δ |
| Supplier Page | Shop |
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