PIM1/2 Kinase Inhibitor VI - CAS 587852-28-6 - Calbiochem
| Name | PIM1/2 Kinase Inhibitor VI - CAS 587852-28-6 - Calbiochem |
|---|---|
| Supplier | EMD Millipore |
| Catalog | 526524 |
| Cas Number | 587852-28-6 |
| Formula | C₁₃H₁₃NO₃S |
| Purity | ≥95% by HPLC |
| Description | A cell-permeable thiazolidinedione compound that acts as a potent, ATP-competitive inhibitor against Pim-1/2 kinases (IC 50 = 150 nM and 20 nM against Pim-1 and Pim-2, respectively) as well as DYRK1α (68% inhibition of DYRK1α and Pim-2 at 5 µM), while exhibiting little or no activity against a panel of 57 other kinases (≤18% inhibition at 5 µM) |
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