Hesperadin - CAS 422513-13-1 - Calbiochem
| Name | Hesperadin - CAS 422513-13-1 - Calbiochem |
|---|---|
| Supplier | EMD Millipore |
| Catalog | 375680 |
| Cas Number | 422513-13-1 |
| Formula | C₂₉H₃₂N₄O₃S |
| Purity | ≥95% by HPLC |
| Description | A cell-permeable indolinone compound that interacts with both the ATP- and the adjacent hydrophobic binding pocket of Aurora B and acts as a rapid and reversible inhibitor of Aurora kinase B activity (IC 50 ~250 nM) with moderate selectivity over Cdk1/B, Cdk2/E and Cdk4/D1 (IC 50 = 1.2, > 10 and > 10 µM) |
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