Name | InSolution™ β-Secretase Inhibitor IV - CAS 797035-11-1 - Calbiochem |
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Supplier | EMD Millipore |
Catalog | 565794 |
Cas Number | 797035-11-1 |
Formula | A10mM(500µg/86.4µL)solutionofβ-SecretaseInhib |
Purity | ≥95% by HPLC |
Description | A cell-permeable isophthalamide compound containing hydroxyethylamine motif that binds to BACE-1 active site and potently blocks its proteolytic activity (IC 50 = 15 nM for BACE-1, human and 29 nM for sAPP_NF in HEK293-APP NFEV cells) |
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