Nimesulide Analog, Compound 76 - CAS 1021926-22-6 - Calbiochem

Name Nimesulide Analog, Compound 76 - CAS 1021926-22-6 - Calbiochem
Supplier EMD Millipore
Catalog 482210
Cas Number 1021926-22-6
Formula C₂₄H₃₂N₂O₄S
Purity ≥95% by HPLC
Description A cell-permeable sulfonanilide that is shown to exhibit an antiproliferative effect against three HER-2-positive breast cancer cell lines, SKBR-3, BT474 and MDA-MB-453 (IC 50 = 0.9, 2.2, and 4.0 µM, respectively), and affects two HER-2-negative breast cancer cell lines, MCF-7 and MDA-MB-231 only at much higher concentrations (IC 50 = 22.1 and 19.6 µM, respectively)
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