Name | Nimesulide Analog, Compound 76 - CAS 1021926-22-6 - Calbiochem |
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Supplier | EMD Millipore |
Catalog | 482210 |
Cas Number | 1021926-22-6 |
Formula | C₂₄H₃₂N₂O₄S |
Purity | ≥95% by HPLC |
Description | A cell-permeable sulfonanilide that is shown to exhibit an antiproliferative effect against three HER-2-positive breast cancer cell lines, SKBR-3, BT474 and MDA-MB-453 (IC 50 = 0.9, 2.2, and 4.0 µM, respectively), and affects two HER-2-negative breast cancer cell lines, MCF-7 and MDA-MB-231 only at much higher concentrations (IC 50 = 22.1 and 19.6 µM, respectively) |
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