MMP Inhibitor V - CAS 223472-31-9 - Calbiochem

Name MMP Inhibitor V - CAS 223472-31-9 - Calbiochem
Supplier EMD Millipore
Catalog 444290
Cas Number 223472-31-9
Formula C₂₂H₂₈N₂O₆
Purity ≥98% by HPLC
Description An orally active non-peptidyl hydroxamate compound that acts as an effective broad-spectrum inhibitor against MMP-2/3/8/9/12/13 (K i = 0.73, 42, 1.1, 2.1, 0.45, and 1.1 nM, respectively), but not MMP-1 (IC 50 = 1.6 µM), MMP-7 (K i = 2.5 µM), or other serine proteases (no activity against chymotrypsin or plasmin at 100 µM)
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