Name | IQ-1 - CAS 331001-62-8 - Calbiochem |
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Supplier | EMD Millipore |
Catalog | 412400 |
Cas Number | 331001-62-8 |
Formula | C₂₁H₂₂N₄O₂ |
Purity | ≥95% by HPLC |
Description | A cell-permeable tetrahydroisoquinolinylidene compound that modulates Wnt/β-catenin signaling by targeting the PR72/130 subunit of PP2A and thereby blocking PP2A/Nkd complex formation, resulting in diminished β-catenin/p300 interaction and a concomitant increase in β-catenin/CBP usage |
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