SIRT2 Inhibitor, Inactive Control, AGK7 - CAS 304896-21-7 - Calbiochem

Name SIRT2 Inhibitor, Inactive Control, AGK7 - CAS 304896-21-7 - Calbiochem
Supplier EMD Millipore
Catalog 566326
Cas Number 304896-21-7
Formula C₂₃H₁₃Cl₂N₃O₂
Purity ≥97% by HPLC
Description A cell-permeable structural isomer of SIRT2 Inhibitor, AGK2 (Cat. No. 566324 ) that selectively inhibits sirtuin 3 over sirtuins 1 and 2 (IC 50 = >5 µM, >50 µM and >50 µM for SIRT3, SIRT1 and SIRT2, respectively) and poorly affects both α-synuclein-mediated toxicity and α-Syn aggregation in α-Syn-H4 cells.
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