PME-1 Inhibitor, AMZ-30 - Calbiochem

Name PME-1 Inhibitor, AMZ-30 - Calbiochem
Supplier EMD Millipore
Catalog 539695
Formula C₁₉H₁₃FN₃O₆S₂
Purity ≥97% by HPLC
Description A cell-permeable sulfonyl acrylonitrile compound that acts as a potent and irreversible inhibitor of protein phosphatase methylesterase-1 (PME-1; IC 50 = 600 nM and 2.5 µM in human cell lysates and in HEK 293T cells, (respectively) with 100-fold greater selectivity over other serine hydrolases; does not function as a general thiol-reactive probe
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