Mer RTK Inhibitor, UNC569 - Calbiochem

• Supplier: EMD Millipore
• Catalog: 445835
• Formula: C₂₂H₂₉FN₆
• Purity: ≥95% by HPLC
• Description: An orally bioavailable pyrazolopyrimidine compound that acts as a potent, reversible and ATP-competitive inhibitor of Mer receptor tyrosine kinase (IC 50 = 2.9 nM; K i = 4.3 nM) with ~10-fold greater selectivity over other TAM family kinases (IC 50 = 37 and 48 nM for Axl and Tyro3, respectively)

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