Casein Kinase I Inhibitor III, PF-4800567 - Calbiochem

Name Casein Kinase I Inhibitor III, PF-4800567 - Calbiochem
Supplier EMD Millipore
Catalog 218719
Formula C₁₇H₁₈ClN₅O₂
Purity ≥99% by HPLC
Description A cell-permeable pyrazolopyrimidinylamino compound that acts as a potent, ATP-competitive and reversible inhibitor of CKIε with ~22-fold greater potency over CKIδ (IC 50 = 32 and 711 nM, respectively) and displays excellent selectivity among 50-kinases, with the only exception of EGFR (69% inhibition at 1 µM)
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