Tankyrase1/2 Inhibitor III - CAS 865565-29-4 - Calbiochem
| Name | Tankyrase1/2 Inhibitor III - CAS 865565-29-4 - Calbiochem |
|---|---|
| Supplier | EMD Millipore |
| Catalog | 575546 |
| Cas Number | 865565-29-4 |
| Formula | C₂₀H₁₉N₅O₃S |
| Purity | ≥99% by HPLC |
| Description | A cell-permeable triazolylthiomethyl-oxadiazole compound that binds TNKS1/PARP5a and TNKS2/PARP5b with high affinity (K d = 79 and 28 nM, respectively), and acts as a potent and reversible TNKS1/2 dual inhibitor (IC 50 = 33 nM TNKS2 in an auto-PARsylation assay) |
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