p38 MAP Kinase Inhibitor IX - CAS 630106-85-3 - Calbiochem
| Name | p38 MAP Kinase Inhibitor IX - CAS 630106-85-3 - Calbiochem |
|---|---|
| Supplier | EMD Millipore |
| Catalog | 506161 |
| Cas Number | 630106-85-3 |
| Formula | C₂₂H₁₇N₇O₂ |
| Purity | ≥95% by HPLC |
| Description | A cell-permeable pyrazolo-pyrimidine compound that acts as a potent ATP-binding pocket-targeting inhibitor against p38α MAP kinase activity (IC 50 = 5 nM; K i = 0.2 nM), while exhibiting little or no activity against a panel of 21 other commonly studied kinases and 5 CYP 450 isozymes (IC 50 ≥40 µM) |
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