EGFR Inhibitor - CAS 879127-07-8 - Calbiochem

Name EGFR Inhibitor - CAS 879127-07-8 - Calbiochem
Supplier EMD Millipore
Catalog 324674
Cas Number 879127-07-8
Formula C₂₁H₁₈F₃N₅O
Purity ≥97% by HPLC
Description A cell-permeable 4,6-dianilinopyrimidine compound that acts as a potent, ATP-competitive, and highly selective inhibitor of EGFR and some EGFR mutants (IC 50 = 21 nM, 63 nM, and 4 nM for EGFRwt, EGFR L858R and EGFR L861Q , respectively) vs
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