MMP-9 Inhibitor II - Calbiochem

Name MMP-9 Inhibitor II - Calbiochem
Supplier EMD Millipore
Catalog 444293
Formula C₁₆H₁₇F₂N₃O₃S
Purity ≥98% by HPLC
Description This compound is a cell-permeable, selective, and reversible thiopyrimidone MMP-9 allosteric inhibitor that binds specifically to the non-catalytic site of MMP-9 at the PEX domain with a K d = 2.1 µM and thereby disrupts MMP-9 homodimerization and its cross-talk with CD44 and the EGFR-MAPK signaling pathway
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