p97 ATPase Activity Inhibitor, DBeQ - Calbiochem

• Supplier: EMD Millipore
• Catalog: 506190
• Formula: C₂₂H₂₀N₄
• Purity: ≥95% by HPLC
• Description: A cell-permeable quinazolinamine compound that inhibits the AAA (ATPase associated with diverse cellular activities) ATPase p97 (IC 50 = 1.6 µM against WT or C522A p97) in a reversible and ATP-competitive ( K i = 3.2 µM) manner, while being at least 50-fold less potent against AAA ATPase NSF (N-methylmaleimide-sensitive factor) or the ATP-dependent chymotrypsin-like activity of proteasome 20S, and exhibiting no significant activity against a panel of ~170 kinases