Akt Inhibitor IV - CAS 681281-88-9 - Calbiochem
| Name | Akt Inhibitor IV - CAS 681281-88-9 - Calbiochem |
|---|---|
| Supplier | EMD Millipore |
| Catalog | 124011 |
| Cas Number | 681281-88-9 |
| Formula | C₃₁H₂₇IN₄S |
| Purity | ≥98% by HPLC |
| Description | A cell-permeable and reversible benzimidazole compound that inhibits Akt phosphorylation/activation presumably by targeting the ATP binding site of a kinase upstream of Akt, but downstream of PI3-K. Shown to block Akt-mediated FOXO1a nuclear export (IC 50 = 625 nM) and cell proliferation (IC 50 <1.25 µM) in 786-O cells |
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