InSolution™ Akt Inhibitor IV - Calbiochem

Name InSolution™ Akt Inhibitor IV - Calbiochem
Supplier EMD Millipore
Catalog 124015
Formula A10mM(1mg/163µl)solutionofAktInhibitorIV(Cat.
Purity ≥98% by HPLC
Description A cell-permeable benzimidazole compound that inhibits Akt phosphorylation/activation presumably by targeting the ATP binding site of a kinase upstream of Akt, but downstream of PI3K. Shown to block Akt-mediated FOXO1a nuclear export (IC 50 = 625 nM) and cell proliferation (IC 50 < 1.25 µM) in 786-O cells
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