Name | InSolution™ Akt Inhibitor IV - Calbiochem |
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Supplier | EMD Millipore |
Catalog | 124015 |
Formula | A10mM(1mg/163µl)solutionofAktInhibitorIV(Cat. |
Purity | ≥98% by HPLC |
Description | A cell-permeable benzimidazole compound that inhibits Akt phosphorylation/activation presumably by targeting the ATP binding site of a kinase upstream of Akt, but downstream of PI3K. Shown to block Akt-mediated FOXO1a nuclear export (IC 50 = 625 nM) and cell proliferation (IC 50 < 1.25 µM) in 786-O cells |
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