c-Met/RON Dual Kinase Inhibitor - CAS 913376-84-8 - Calbiochem
| Name | c-Met/RON Dual Kinase Inhibitor - CAS 913376-84-8 - Calbiochem |
|---|---|
| Supplier | EMD Millipore |
| Catalog | 448104 |
| Cas Number | 913376-84-8 |
| Formula | C₃₁H₂₉FN₄O₅ |
| Purity | ≥95% by HPLC |
| Description | A cell-permeable quinoline compound that acts as a potent inhibitor against the kinase activities of HGF (Cat. No. 375228) receptor c-Met and MSP (Macrophage Stimulating Protein) receptor RON (IC 50 = 4 and 9 nM, respectively), while exhibiting much weaker potency toward Lck, Tie2, Src, BTK, IGFR, or VEGFR2 (IC 50 = 160, 400, 410, 710, 1000, and 1900 nM, respectively), and little or no activity against B-Raf and more than 20 other kinases IC 50 >1 µM) |
| Supplier Page | Shop |
Product images
