STAT3 Inhibitor VII - CAS 1041438-68-9 - Calbiochem

Name STAT3 Inhibitor VII - CAS 1041438-68-9 - Calbiochem
Supplier EMD Millipore
Catalog 573103
Cas Number 1041438-68-9
Formula C₁₉H₇F₇N₂O₃
Purity ≥95% by HPLC
Description A cell-permeable dihydroquinoline compound that potently and specifically inhibits cellular JAK1/JAK2/TYK2/STAT3 activation (IC 50 against U266 constitutive STAT3 Y705 phosphorylation =170 nM) as well as the transcription of STAT3 target genes, while exhibiting little effects against pathways involved in Akt/mTOR, Erk1/2, or STAT5 activation
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