Name | STAT3 Inhibitor VII - CAS 1041438-68-9 - Calbiochem |
---|---|
Supplier | EMD Millipore |
Catalog | 573103 |
Cas Number | 1041438-68-9 |
Formula | C₁₉H₇F₇N₂O₃ |
Purity | ≥95% by HPLC |
Description | A cell-permeable dihydroquinoline compound that potently and specifically inhibits cellular JAK1/JAK2/TYK2/STAT3 activation (IC 50 against U266 constitutive STAT3 Y705 phosphorylation =170 nM) as well as the transcription of STAT3 target genes, while exhibiting little effects against pathways involved in Akt/mTOR, Erk1/2, or STAT5 activation |
Supplier Page | Shop |