p38 MAP Kinase Inhibitor VIII - CAS 321351-00-2 - Calbiochem
| Name | p38 MAP Kinase Inhibitor VIII - CAS 321351-00-2 - Calbiochem |
|---|---|
| Supplier | EMD Millipore |
| Catalog | 506163 |
| Cas Number | 321351-00-2 |
| Formula | C₂₀H₁₆BrClN₂O |
| Purity | ≥97% by HPLC |
| Description | A cell-permeable aminobenzophenone compound that acts as a potent, ATP-binding pocket-targeting inhibitor against p38α and p38β 2 (82% and 93% inhibition with 1 µM inhibitor, respectively; IC 50 of p38α inhibition = 40 nM) with little activity against a panel of 57 other kinases, including p38γ, p38δ, Erk1/2, and JNK1 |
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