SRT1720 - CAS 925434-55-5 - Calbiochem

• Supplier: EMD Millipore
• Catalog: 567860
• Cas Number: 925434-55-5
• Formula: C₂₅H₂₃N₇OS
• Purity: ≥97% by HPLC
• Description: A cell-permeable quinolinecarboxamide compound that is shown to inhibit the mitochondrial SIRT3 in a substrate AceCS2- (Acetyl-CoA synthetase 2) competitive ( K i = 0.56 µM; K m = 2.44 µM; V max = 173.35 µM/min), but NAD + -uncompetitive ( K i = 0.34 µM; K m = 280 µM; V max = 0.86 µM/min), manner, indicative of NAD + binding as a prerequisite for inhibitor binding

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