Nicotinamide Phosphoribosyltransferase Inhibitor, FK866 - CAS 658084-64-1 - Calbiochem
| Name | Nicotinamide Phosphoribosyltransferase Inhibitor, FK866 - CAS 658084-64-1 - Calbiochem |
|---|---|
| Supplier | EMD Millipore |
| Catalog | 481908 |
| Cas Number | 658084-64-1 |
| Formula | Suppliedasa50mM(2mg/102.17µl)solutioninDMSO. |
| Purity | ≥97% by HPLC |
| Description | A cell-permeable pyridinylacrylamide compound that acts as a selective, allosteric NAPRT/NAMPT (nicotinamide phosphoribosyltransferase) inhibitor (K i = 0.4 nM for the enzyme/substrate complex; K i ′ = 0.3 nM for the free enzyme), while exhibiting no effect toward NPRT (nicotinic acid phosphoribosyltransferase) activity (82% inhibition of NAPRT activity at 10 nM vs no inhibition of NPRT activity at 1 µM in K-562 extract) |
| Supplier Page | Shop |
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