Name | PDGFR Tyrosine Kinase Inhibitor VII - CAS 251356-45-3 - Calbiochem |
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Supplier | EMD Millipore |
Catalog | 521237 |
Cas Number | 251356-45-3 |
Formula | C₂₄H₂₂N₂O₃ |
Purity | ≥97% by HPLC |
Description | A cell-permeable indolinone compound that acts as a potent, ATP site-targeting PDGFR inhibitor (IC 50 = 10 nM against PDGFRβ), while affecting Flk-1/KDR/ VEGFR2, FGFR1, and EGFR only at much higher concentrations (IC 50 = 0.14, 2.29, and >100 µM, respectively) |
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