PDGFR Tyrosine Kinase Inhibitor VII - CAS 251356-45-3 - Calbiochem

Name PDGFR Tyrosine Kinase Inhibitor VII - CAS 251356-45-3 - Calbiochem
Supplier EMD Millipore
Catalog 521237
Cas Number 251356-45-3
Formula C₂₄H₂₂N₂O₃
Purity ≥97% by HPLC
Description A cell-permeable indolinone compound that acts as a potent, ATP site-targeting PDGFR inhibitor (IC 50 = 10 nM against PDGFRβ), while affecting Flk-1/KDR/ VEGFR2, FGFR1, and EGFR only at much higher concentrations (IC 50 = 0.14, 2.29, and >100 µM, respectively)
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